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Behrend, L., Milne, D., Campbell, L., D. W. Meek, Deppert, W.,and Knippschild, U (2000). IC261,
a specific inhibitor of the protein kinases casein kinase
1-delta and –epsilon, triggers the mitotic
checkpoint and in induces p53-dependent postmitotic
effects.
Behrend, L., Stöter, M, Kurth, M., Rutter, G., Heukeshoven, J., and Knippschild, U. (2000) Interaction of casein kinase 1 delta (CK1d with post Golgi structures, microtubules and the spindle apparatus. Eur. J. Cell Biol. 79: 240-251
Janus, F., Albrechtsen, N., Knippschild, U., Wiesmüller, L., Grosse, F., and Deppert, W. (1999) Different regulation of the p53 core domain activities 3'-to-5' exonuclease and sequence-specific DNA binding. Mol. Cell. Biol. 19: 2155-68
Meek, D., Campbell, L., Hall, S.R., Jardine, L.J., Knippschild, U., and D. Milne. (1998) Phosphorylation of the p53 tumour suppressor protein by stress- and DNA damage-activated protein kinases. Cell Growth and Oncogenesis, Birkhäuser Verlag: 109-115
Meek, D., Campbell, L., Jardine, L.J., Knippschild, U., McKendrick, L., and Milne, D. M. (1997) Multisite phosphorylation of p53 by protein kinases inducable by p53 and DNA damage Biomedical Society Transactions 25: 416-419
Knippschild, U., Milne, D. M., Campbell, L., DeMaggio, T., Christenson, E., Hoekstra, M. F. and Meek, D. (1997) p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of the casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs. Oncogene 15: 1727-1737
Henning, W., Rohaly, G., Kolzau, T., Knippschild, U., Maacke, H., and Deppert, W. (1997) MDM2 is a target of simian virus 40 in cellular transformation and during lytic infection. J. Virol. 71: 7609-7618
Knippschild, U., Milne, D. M., Campbell, L., and Meek, D. (1996) p53 N-terminus-targeted protein kinase activity is stimulated in response to wild type p53 and DNA damage. Oncogene 13:1387-93
Knippschild, U., Oren, M., and Deppert, W. (1996) Abrogation of wild-type p53 mediated growth-inhibition by nuclear exclusion. Oncogene 12:1755-65
Stürzbecher, H-W., Donzelmann, B., Henning, W., Knippschild, U., and Buchhop, S. (1996) p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction. EMBO J. 15:1992-2002
Knippschild, U., Kolzau, T., and Deppert, W. (1995) Cell-specific transcriptional activation of the mdm2-gene by ectopically expressed wild-type form of a temperature-sensitive mutant p53. Oncogene 11: 683-690
Zerrahn, J., Knippschild, U., Winkler, T., and Deppert, W. (1993) Independent expression of the transforming N-terminal domain of SV40 large T antigen from an alternatively spliced third SV40 early mRNA. EMBO J. 12: 4739-4746
Patschinsky, T., Knippschild, U., and Deppert, W. (1992) Species-specific phosphorylation of mouse and rat p53 in simian virus 40 transformed cells. J. Virol. 66: 3846-3859
Deppert, W., Kurth, M., Graessmann, M., Graessmann, A., and Knippschild, U. (1991) Altered Phosphorylation at specific sites confers a mutant phenotype to SV40 wild-type large T antigen in a flat revertant of SV40 transformed cells. Oncogene 6: 1931-1938
Knippschild, U., Kiefer, J., Patschinsky, T., and Deppert, W. (1991) Phenotype-specific phosphorylation of simian virus 40 tsA mutant large T antigens in tsA N-Type and A-Type transformants. J.Virol. 65: 4414-4423
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